Depression leads to low sex drive and interest. This is due to the condition and side effects of the medications as well. Some medications cause difficulty to perform and inability to achieve orgasm.

These situations affect both the person with the condition and his or her partner. Partners should be patient and helpful. Partners have to cope with the situation encouraging the person with condition.
These sex problems worsen the depression further.

People with the bipolar should remember that they will gain back their sexuality one day. During mania as well as once they recover from depression, they will realise this fact. It is very much difficult for married people to stay married unless they get very understanding and helpful partners.

For the unmarried it is very hard because they can not share all these details with causal relationships.